Humanities background

What are the "main" differences between getting a degree (e.g., MI) from an "iSchool" vs. an getting an MDes or MFA from an IxD specific program? And which would be better for someone with a humanities background?

Hello!

I'm new to this site and have been reading a bunch about master's programs for IxD since I've been preparing to apply for the Fall 2012 term. This whole field is relatively new to me (I only found out about it about half a year ago) and at first I was concentrating on strictly IxD programs (like at CMU or U of Wash), but have lately found threads where iSchools were mentioned as being good because it doesn't require a design background, so I started taking a look at those.