Jeffrey Zeldman says Intertwingled is about information architecture:
"In the information age, we are all information architects, says Morville in this fresh and fascinating take on the discipline he played a huge part in creating. Drawing on nature, culture, history, and science, plus decades of deep personal experience helping major clients, Morville finds new and profound meaning in the business of helping users to find their way."
Brenda Laurel says Intertwingled is about interaction design:
A couple days ago, I posted an article on UX Magazine about inexact design. It follows from the way I have been working for a long while, and some presentations I've given, but after reading some other work on electronics design and service availability (and talking with some other smart UX folks) I codified it a bit more.